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GSK3368715 dihydrochloride

Glpbio

Catalog No：GC36192-10mM (in 1mL DMSO) CAS No.：1628925-77-8 MDLNo： Brand:Glpbio purity： 特性： Purpose:GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) 是具有口服活性的，可逆的，SAM 非竞争性 I 型蛋白精氨酸甲基转移酶 (PRMTs) 抑制剂 (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8))。GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) 导致精氨酸甲基化状态的转变，改变了外显子的使用，具有很强的抗癌活性。DMSO: 250 mg/mL (568.88 mM)

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Product Overview

Product Name	GSK3368715 dihydrochloride
CAS	1628925-77-8
Formula	C₂₀H₄₀Cl₂N₄O₂
MW	439.46
Storage condition	Store at 4°C, stored under nitrogen

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History

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